Lines of Research, Funding and Scientific Collaborations.
Study of the intertissular communication between perivascular adipose tissue and artery as the origin of obesity-associated vascular dysfunction
The loss of function and the change in the secretome of the adipose tissue surrounding blood vessels precedes and favors the onset of endothelial dysfunction.
Transplantation of brown adipose tissue as an anti-obesity tool after in vitro activation.
The thermogenic capacity of obese adults is practically nonexistent, which is why we propose the transplantation of in vitro activated brown adipocytes as an anti-obesity therapy.
Transplantation of brown adipose tissue as an anti-obesity tool after in vitro activation.
The thermogenic capacity of obese adults is practically nonexistent, which is why we propose the transplantation of in vitro activated brown adipocytes as an anti-obesity therapy.
Search for differential biomarkers between morbidly obese patients with distinct metabolic profiles
Our goal is to find markers that allow us to understand what protects a percentage of morbidly obese patients who do not develop associated diseases, since this would enable individualization and prioritization of therapeutic actions.
Activation of the protective branch of the renin-angiotensin system to prevent vascular dysfunction associated with obesity.
The goal is to counteract the negative effects of renin-angiotensin system activation in obesity through the use of specific AT2 receptor agonists.
Activation of the protective branch of the renin-angiotensin system to prevent vascular dysfunction associated with obesity
The goal is to counteract the negative effects of renin-angiotensin system activation in obesity through the use of specific AT2 receptor agonists.
Funding
Active Funding
Activation of the AT2 receptor as a treatment for vascular alterations associated with obesity: role of perivascular adipose tissue. Ministerio de Ciencia e Innovación. PID2021-125790OB-I00. PI: Beatriz Somoza. 2022-2026. Total Amount: 108.000,00 €.
Transplantation of in vitro activated brown adipocytes with compound 21 as an anti-obesity therapy. Ministerio de Ciencia e Innovación. PID2020-114343GA-I00. PI: Martín Alcalá. 2021-2025. Total Amount: 121.000,00 €.
Previous Funding
Anti-obesity cellular therapy through transplantation of brown adipocytes activated by compound 21. Banco Santander-Universidad CEU San Pablo. FUSP-PPC-19-C5B625BA. PI: Marta Viana. 2020-2022. Total Amount: 15.000,00 €.
Crosstalk between hypothalamic astrocytes and perivascular adipose tissue in energy metabolism and cardiovascular function: impact of dietary modifications. Ministerio de Economía y Competitividad. BFU2017-82565-C2-2-R. PI: Soledad Fernández Alfonso y Beatriz Somoza Hernández. 2018-2021. Total Amount: 90.750,00€
Search for differential markers in patients with morbid obesity and different metabolic profiles. Banco Santander-Universidad CEU San Pablo. FUSP-BS-PPC-USP02/2017. PI: Martín Alcalá. 2017-2019. Total Amount: 15.000,00 €.
Study of the mechanisms involved in the development of obesity-associated arterial stiffness: role of the AT2 receptor in perivascular adipose tissue. Fundación Universitaria San Pablo CEU/Banco Santander. FUSP-BS-PPC-USP03/2017. PI: Marta Gil Ortega. 2017 – 2019. Total Amount: 15000€.
Scientific Collaborations
We firmly believe in collaboration between research groups as the only effective way to advance in Science.
These are some of our friends:
